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Although cyanocobalamin is more readily absorbed, much of it is excreted through the urine before it can reach the cells Cyanocobalamin vs Hydroxocobalamin In comparison to hydroxocobalamin, cyanocobalamin has a significantly worse absorption rate and storability, which is why today mostly hydroxocobalamin is used in B12 injections

For women with known PCOS or other reproductive endocrine conditions, baseline and follow-up assessments of metabolic and reproductive parameters can help distinguish medication effects from underlying disease progression

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The medicinal form depends on how well it is absorbed in the body and factors such as age, genetics, and the condition of the digestive system

A few patients may experience pain after injection of hydroxocobalamin